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一项发表在《信号转导与靶向治疗》期刊上的研究,以金银花中富含的植物微小RNA MIR2911为模型,揭示了不同的生产工艺如何影响草药的效力。研究人员发现,传统的“水煎法”能够有效保留MIR2911及其抗病毒活性。相比之下,现代生产中普遍采用的乙醇提取法,则会去除大部分MIR2911,并显著降低其生物活性。这项研究从生产工艺的角度对现有认知提出了挑战,探讨了在实际的采集、干燥、提取和灭菌过程中,具有功能的植物RNA会发生怎样的变化。

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